Understanding the Differences and Benefits

In the rapidly evolving landscape of cannabis and hemp-derived products, cannabinoids like CBG (cannabigerol) and CBD (cannabidiol) have gained significant attention for their potential therapeutic properties. While both are derived from the cannabis plant, CBG and CBD differ in their chemical compositions, potential benefits, and modes of action within the body. Understanding these differences is key to navigating the expanding market of cannabinoid-based products and making informed choices about their use.

What are CBG and CBD?

Cannabigerol (CBG):
CBG is often referred to as the “mother cannabinoid” because it’s considered a precursor from which other cannabinoids like THC and CBD are synthesized. It’s typically found in low concentrations in cannabis plants, and its extraction process involves harvesting the plant at an early stage of growth.

At Kauai Hemp Company, we specialize in organically cultivating strains of cannabis that are CBG-dominant; ie. growing cannabis cultivars that have high concentrations of CBG.

Cannabidiol (CBD):

CBD is one of the most abundant cannabinoids found in cannabis plants, second only to THC (tetrahydrocannabinol). Unlike THC, CBD is non-intoxicating and doesn’t produce a “high.” CBD is commonly extracted from hemp, a variety of cannabis that contains less than 0.3% THC.

Chemical Structure and Mode of Action

CBG interacts with the endocannabinoid system (ECS) by binding directly to CB1 and CB2 receptors, though not as strongly as THC. It also influences non-cannabinoid receptors, potentially impacting serotonin receptors involved in mood regulation.

CBD works indirectly with the ECS by enhancing the body’s endocannabinoids, such as anandamide, and inhibiting enzymes that break them down. CBD’s effects extend beyond the ECS, influencing other receptor systems like serotonin, vanilloid, and adenosine receptors.

Key Differences & Benefits between CBG and CBD

Chemical Composition:

  • CBG is the precursor to CBD, THC, and other cannabinoids.
  • CBD is derived directly from CBDA (cannabidiolic acid) through decarboxylation.

Concentration in Plants:

  • CBG is present in lower concentrations in mature cannabis plants.
  • CBD is relatively abundant in mature cannabis plants.

Interactions with Receptors:

  • CBG interacts directly with cannabinoid receptors.
  • CBD modulates endocannabinoids and interacts with various non-cannabinoid receptors.

Daytime vs Nighttime Use:

  • Daytime: CBG is ideal for supporting relaxation and maintaining a balance in your body and mind throughout the day. While CBG and CBD both have a lovely calming effect, CBG is especially useful for managing everyday stress while navigating day-to-day obstacles.*
  • Nighttime: CBD is ideal for evening use due to its ability to support healthy sleep cycles when dealing with occasional sleeplessness. CBD is also an incredible aid in easing muscles after exercise and will leave you feeling refreshed and rejuvenated.*


  • CBG is ideal for supporting relaxation.
  • Helps maintain a balanced mind and body.
  • CBG is especially useful for managing everyday stress while navigating day to day obstacles.


  • CBD is ideal for evening use.
  • Supports healthy sleep cycles when dealing with occasional sleeplessness.
  • CBD can aid in easing muscles after exercise and will leave you feeling refreshed and rejuvenated.

How to Choose Between CBG and CBD Products?

When considering CBG or CBD products, several factors should be taken into account:

Intended Use:

Determine your specific health goals or concerns and research which cannabinoid may be more suitable.

Product Quality:

Look for products from reputable brands that provide third-party lab testing for potency and purity.

Dosage and Potency:

Consider the concentration of CBG or CBD in the product and start with lower doses to assess tolerance and effects.

While CBG and CBD are both cannabinoids derived from cannabis plants, they exhibit distinct chemical properties and mechanisms of action.

Ultimately, the choice between CBG and CBD products depends on individual health needs and preferences. As research continues to unfold, a nuanced understanding of these cannabinoids will facilitate informed decisions and foster the responsible use of cannabinoid-based products.